Ketu in Cancer – South Node in Cancer:
We have a great gift of soul with the South Node in Cancer. Inner nourishment and security is what we want, and with South Node in the 4th we may be jolted out of our cocoon. Unexpected moves and/or career changes may threaten our security. We may be forced to give up protecting our shyness by learning how to cope with others on harsher turf. Pressing toward the North Node can feel threatening, especially since it lies in Saturn ruled Capricorn. But the reward for striving toward the 10th house may be a new found confidence and the financial security of a lucrative career. (Source).